Martha Alston (Ellen DeGeneres) is a single woman working at a television talk show. When her younger sister gets married, everyone's wondering when Martha is going to meet Mr. Right and tie the knot. When by chance, Martha meets a handsome stranger named Whitman Crawford (Bill Pullman), the two fall madly in love with each other. But soon Martha discovers little quirks in Whitman, little quirks that become horrifying nightmares. But by the time Martha realizes that she must break up with him, it'll take more than subtle hints to make him go away. She'll have to get into the most outrageous predicaments to rid herself of Mr. Wrong.